Chimeric polynucleotide

WebNov 12, 2024 · This invention encompasses RNAi molecules for suppressing DNA encoding GST-π, ribozymes, antisense nucleic acids, DNA/RNA chimeric polynucleotides, and vectors for expressing them, and dominant negative variants of GST-π. WebDec 3, 2004 · The term “mutated or chimeric gene” is used to indicate that mutated or chimeric polynucleotides are obtained at a high frequency by using the method …

US20240204152A1 - Chimeric polynucleotides - Google …

WebWO2014132671A1 PCT/JP2014/001159 JP2014001159W WO2014132671A1 WO 2014132671 A1 WO2014132671 A1 WO 2014132671A1 JP 2014001159 W JP2014001159 W JP 2014001159W WO 2014132671 A1 WO201 WebU.S. Patent Application US20160108395A1 for chimeric single-stranded polynucleotides and double-stranded antisense agents useful for modifying the expression of a target gene by means of an antisense effect are disclosed. The chimeric single-stranded antisense polynucleotide and double-stranded antisense agents comprise a central nucleotide … how is the chief executive chosen https://gatelodgedesign.com

CHIMERIC SINGLE-STRANDED ANTISENSE POLYNUCLEOTIDES …

WebJul 7, 2016 · The chimeric polynucleotide of any of the preceding claims wherein the polypeptide is selected from the group consisting of biologics, antibodies, vaccines, … WebThe invention relates to compositions and methods for the preparation, manufacture and therapeutic use of chimeric polynucleotide molecules, which allow for customized … how is the chemical symbol determined

JP2024040151A - Chimeric antigen receptor targeting cancer

Category:WO/2024/057750 CHIMERIC PROTEIN AND EXPRESSION SYSTEM

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Chimeric polynucleotide

Chimera oligonucleotide and its utilization for obtaining transcripts ...

WebThe polynucleotide obtained in step (b) and a polynucleotide encoding the CyaC protein may be combined in a construct in such a way that following said combination, the obtained chimeric polynucleotide comprises or contains, from 5' end to 3' end, the polynucleotide construct of step (b) followed by a polynucleotide construct encoding a CyaC ... WebThe chimeric TNFα is therefore useful in methods for inducing apoptosis of a cell expressing a TNFα receptor, inducing activation of an immune system cell and treating neoplastic cells, by introducing into the cell of interest an isolated polynucleotide sequence encoding a chimeric TNFα that is expressed on the surface of the cell.

Chimeric polynucleotide

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WebThe present invention relates to the field of plant molecular biology and plant genetic engineering, and polynucleic acid molecules useful for gene expression in plants. Specifically, the present invention discloses chimeric polynucleic acid molecules that function as promoters in plant cells. WebJul 7, 2016 · We claim: 1. A chimeric polynucleotide encoding a polypeptide, said chimeric polynucleotide having a sequence comprising Formula I, 5′[A n] x-L1-[B o] y-L2-[C p] z-L3 3′ I wherein: each of A and B independently comprise a region of linked nucleosides; C is an optional region of linked nucleosides; at least one of regions A, B, or …

WebSep 26, 1995 · A chimera oligonucleotide is provided that can be used in a process for obtaining transcripts and/or amplification of a target sequence of a nucleic acid, ... An oligonucleotide sequence is called "DNA type" if it is comprised of DNA or if it is a modified polynucleotide sequence that, in addition to the nucleic acid strand hybridization ... WebChimeric Polynucleotide Regions. In some embodiments, chimeric polynucleotides may be designed to comprise regions, subregions or parts which function in a similar …

WebDec 4, 2024 · Chimeric nucleases enable genome editing in eukaryotic cell. Targeted genome editing with the hope of treating and curing diseases … WebWhole and partially modified phosphorothioate oligodeoxynucleotides (ODN) were found to directly inhibit T4 polynucleotide kinase (PNK) activity, while phosphodiester ODN …

WebPolynucleotide definition, a sequence of nucleotides, as in DNA or RNA, bound into a chain. See more.

WebKind Code: A1 The present invention provides compositions comprising genetically modified effector cells comprising polynucleotides encoding chimeric antigen receptors that can be used in adoptive cell therapy for the treatment of cancer, infectious diseases, autoimmune diseases and degenerative diseases. do. A cell comprising a nucleic acid encoding a … how is the chromeseed backbling reactiveWebDec 12, 2001 · To induce immune responses that might be therapeutic as well as prophylactic for PV infection, we constructed chimeric polynucleotide vaccines incorporating the L1 capsid gene (pH6L1Δ) with segments of E7, an non-structural protein of PV found abundantly in infected cells, added to the C terminus. how is the chief executive chosen in nigeriaWebThe chimeric polynucleotide may contain or encode one or more long noncoding RNA (IncRNA, or lincRNA) or portion thereof, a small nucleolar RNA (sno-RNA), micro … how is the chip program fundedWebBR-0112566-A chemical patent summary. how is the chikungunya virus transmittedWebInhibition depended on the number and type of modified internucleotide linkages: a 20-mer phosphorothioate ODN had an IC50 of 21 nM, while a chimeric ODN with seven phosphorothioate linkages and an identical sequence showed no inhibition. how is the christian church organizedWebBR-0112566-A chemical patent summary. how is the chrisley family doingWeb[0006] These studies are disclosed in, for example, Ribostem Limited in United Kingdom patent application serial number 0316089.2 filed on July 9, 2003 now abandoned, PCT applicat how is the child tax credit calculated